Comment on the Paper by Kamel et al. Entitled ‘Primary Cytomegalovirus Infection in Pregnant Egyptian Women Confirmed by Cytomegalovirus IgG Avidity Testing'
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Comment on the Paper by Kamel et al. Entitled ‘Primary Cytomegalovirus Infection in Pregnant Egyptian Women Confirmed by Cytomegalovirus IgG Avidity Testing’
Dear Editor, The recent report by Kamel et al. [1] on primary cytomegalovirus infection in pregnant women is very interesting. The authors noted that ‘women who were IgM positive had no primary CMV infection in the index pregnancy as evidenced by the high CMV IgG avidity testing’ [1] . In fact, the usefulness of the IgG avidity test was previously reported by Seo et al. [2] , who noted that thi...
متن کاملPrimary Cytomegalovirus Infection in Pregnant Egyptian Women Confirmed by Cytomegalovirus IgG Avidity Testing
OBJECTIVE To determine the frequency of primary cytomegalovirus (CMV) infection in pregnant Egyptian women using CMV IgG avidity testing. SUBJECTS AND METHODS A cross-sectional study was conducted at Suez Canal University Hospital, Ismailia, Egypt. A total of 546 pregnant women, presenting for routine antenatal screening, were tested for CMV IgG and IgM using a commercially available enzyme-l...
متن کاملClinical Significance of IgG avidity testing and other considerations in the diagnosis of congenital cytomegalovirus infection
Human cytomegalovirus (CMV) is a member of the herpesviridae family. It is a double stranded, enveloped and ubiquitous DNA virus that rarely causes disease in healthy individuals yet can cause serious diseases in the fetus and in immunosuppressed individuals [1]. Most CMV infections are inapparent, but the virus can cause a wide range of diseases in susceptible individuals. Fetal CMV infection ...
متن کاملCytomegalovirus: should we screen pregnant women for primary infection?
Congenital cytomegalovirus (CMV) is a leading cause of neonatal morbidity, affecting ~0.5 to 1% of infants born each year. Primary maternal infection during early pregnancy is the greatest risk factor for severe neonatal morbidity/mortality. The current recommendation from national organizations advises against routine screening of pregnant women for primary infection. Recent advancements in di...
متن کاملValue of cytomegalovirus (CMV) IgG avidity index for the diagnosis of primary CMV infection.
This study assessed the diagnostic value of the cytomegalovirus (CMV)-specific IgG avidity index (AI) for pregnant women without a history of CMV seroconversion. Sera were studied from 40 women with CMV seroconversion (group I), 70 with past CMV infection (group II), 10 (20 sera) with serologic reactivation (group III), and 41 with CMV-specific IgM without proven seroconversion (group IV). Sera...
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ژورنال
عنوان ژورنال: Medical Principles and Practice
سال: 2014
ISSN: 1011-7571,1423-0151
DOI: 10.1159/000365446